The Gut-Wrenching Truth: Pathophysiology and Clinical Features of Intestinal Hyperpermeability Syndrome

The microbes associated with the gut are called the gut microbiota. There are about 1000 species of bacteria weighing up to 1-2 kg in the human gut. Microbial diversity increases with age until it is stable. Humans have evolved to live with them and have learned to play their role in the body. Dysbiosis in the gut microbiota causes various ailments, disorders and diseases in humans. And all of this is due to the increased intestinal permeability caused by gut microbiota dysbiosis. The present review discusses some pathophysiological and clinical symptoms of leaky gut syndrome, a highly controversial but logical and relevant topic of medical microbiology and gastroenterology in humans.