Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of <i>SOAT2</i> RNA methylation

The findings highlight the critical role of NSUN2 in driving HCC progression through the regulation of m5C modification on SOAT2. These findings present potential molecular markers for HCC diagnosis and therapeutic targets for its treatment.

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Publication Details

Journal
Cancer Communications
Published
2025-04-14
DOI
https://doi.org/10.1002/cac2.70023
Citations
13
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
10.48

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article

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Fang Guo, Caixia Xu, Jinhua Jiang, Dan Cui et al.
13 citations
Cancer Communications
RNA modifications and cancer
10.48
article

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Fang Guo, Caixia Xu, Jinhua Jiang, Dan Cui, Tinghua Yan, Feng Liu, Jiachang Chi
article en
13 citations

Abstract

The findings highlight the critical role of NSUN2 in driving HCC progression through the regulation of m5C modification on SOAT2. These findings present potential molecular markers for HCC diagnosis and therapeutic targets for its treatment.

Cancer CommunicationsVol. 45(7)
Jinan University (CN), Shanghai Jiao Tong University (CN), Renji Hospital (CN), Jinan University (LB)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 1%
RNA modifications and cancer
10.48
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