Characterization of a novel cell line established from mice gastrointestinal stromal model by chemical induction
We firstly established a mGSTc01 cell line derived from C57BL/6 J mice GIST tumor offers, which closely mimicking human disease characteristics. It is a potent platform for investigating tumor microenvironment of GIST in mice model, and provides a novel way for new therapeutic discoveries in GIST.
Authors
- Yiran Zhang (ORCID: https://orcid.org/0000-0002-0955-2368)
- Hui Ding (ORCID: https://orcid.org/0000-0002-2277-3894)
- Xiaoxu Zhao (ORCID: https://orcid.org/0000-0001-9746-3770)
- Shenghui Qiu (ORCID: https://orcid.org/0000-0002-4221-0642)
- Zhan Zhao (ORCID: https://orcid.org/0000-0002-0385-5595)
- Yun-long Pan (ORCID: https://orcid.org/0000-0002-7434-6560)
- Yangzhi Hu (ORCID: https://orcid.org/0000-0003-2600-1442)
- Shijin Liu (ORCID: https://orcid.org/0000-0002-6194-9557)
- Xiangwei Zhang (ORCID: https://orcid.org/0000-0002-8679-6817)
- Jinghua Pan (ORCID: https://orcid.org/0000-0003-3741-3397)
- Jiashuai He (ORCID: https://orcid.org/0000-0003-0840-9348)
- Zuyang Chen
- Xiaobo Li (ORCID: https://orcid.org/0000-0001-9031-4684)
- Hanyang Guan
- Simin Luo
- Lu Wang (ORCID: https://orcid.org/0009-0006-0439-5160)
- Jie Cao (ORCID: https://orcid.org/0000-0001-6498-7172)
- T. Mo
Institutions
- Jinan University (CN)
- Guangzhou First People's Hospital (CN)
- First Affiliated Hospital of Jinan University (CN)
- Xiangnan University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1016/j.tranon.2025.102388
- Primary Topic
- Gastrointestinal Tumor Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00