Composites of Chitosan for Biomedical Applications

Chitosan (CS) is a cationic polysaccharide that consists of jumble distributed units of N-acetyl-D-glucosamine (acetylated unit) and β-(1→4)-linked D-glucosamine (deacetylated unit). CS has gained significant importance in the field of biomedicine due to its non-toxicity, biodegradability, and biocompatibility properties. It has numerous potential applications, including in the development of bandages that can reduce bleeding and serve as antibacterial agents, as well as DDSs that can transport medication across the skin and BBB. CS can be used alone or in amalgamation with antibiotics and extracts to create antimicrobial wound dressings that are effective in treating infections. Overall, CS and its derivatives hold great promise for biomedical implicatives, particularly in wound healing and DD. Due to its qualities, CS-based NPs are being studied as possible DDS against diseases like Leishmaniasis, Bacterial Diseases, and Cancer. Throughout the chapter we will have an overview of these properties of CS, their possible applications in the biomedical field and their possible role against these diseases.