Primary Vitreoretinal Lymphomas: A Diagnostic Challenge – Report of Two Recent Cases with Retinal Biopsies and Molecular Investigations in Halifax, Nova Scotia

PVRLs are rare, and establishing the diagnosis is difficult. The traditional use of vitreous cytology has its limitations. Recent molecular advances, in particular the detection of MYD88 mutation, are extremely helpful in confirming the diagnosis, but in certain cases, retinal biopsies may still be required.

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Publication Details

Journal
Ocular Oncology and Pathology
Published
2025-04-14
DOI
https://doi.org/10.1159/000545823
Primary Topic
CNS Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Primary Vitreoretinal Lymphomas: A Diagnostic Challenge – Report of Two Recent Cases with Retinal Biopsies and Molecular Investigations in Halifax, Nova Scotia

Sylvia Pasternak, Amr Zaki, Bonnie He, R. Rishi Gupta et al.
Ocular Oncology and Pathology
CNS Lymphoma Diagnosis and Treatment
article

Primary Vitreoretinal Lymphomas: A Diagnostic Challenge – Report of Two Recent Cases with Retinal Biopsies and Molecular Investigations in Halifax, Nova Scotia

Sylvia Pasternak, Amr Zaki, Bonnie He, R. Rishi Gupta, Korolos Sawires, Caroline Alice Guinard
article en

Abstract

PVRLs are rare, and establishing the diagnosis is difficult. The traditional use of vitreous cytology has its limitations. Recent molecular advances, in particular the detection of MYD88 mutation, are extremely helpful in confirming the diagnosis, but in certain cases, retinal biopsies may still be required.

Ocular Oncology and PathologyVol. 11(2)
Dalhousie University (CA)
No poverty
Openalex Percentile: Top 87%
CNS Lymphoma Diagnosis and Treatment
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