Causal effect of three autoimmune diseases on brain functional networks and cerebrospinal fluid metabolites to underlie the pathogenesis of autoimmune psychosis: a two-sample mendelian randomization analysis
Our study pinpoints important brain functional networks and CSF metabolites potentially implicated in the pathogenesis of psychiatric disorders associated with autoimmune diseases and highlights critical brain regions for the development of novel therapeutics.
Authors
- R Wang
- Chengping Wen
- Lin Huang (ORCID: https://orcid.org/0000-0002-8036-8408)
- Qiao Wang (ORCID: https://orcid.org/0000-0002-1823-5516)
- Min Chen (ORCID: https://orcid.org/0000-0002-8722-6883)
- Weiman Shi
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1186/s12967-025-06113-1
- Citations
- 1
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.58
Funders
- National Natural Science Foundation of China
- Zhejiang Traditional Chinese Medicine Administration
- Natural Science Foundation of Zhejiang Province