First identification and whole-genome characterization of human-associated Enterobacter roggenkampii and Enterobacter sichuanensis carrying blaIMI-4 carbapenemase in Costa Rica
The limited global distribution of the bla<sub>IMI-4</sub> variant, along with its identification in two distinct bacterial species in Costa Rica within integrative mobile elements, underscores the critical need for regular antibiotic resistance surveillance using next-generation sequencing technologies. This study demonstrates that this practice allows the timely detection of novel or rare mechanisms of antibiotic resistance.
Authors
- Manuel Ramírez-Cardoce (ORCID: https://orcid.org/0000-0001-5337-1030)
- Daniel Cascante-Serrano (ORCID: https://orcid.org/0000-0002-2928-8365)
- Ricardo Pachón Gutiérrez (ORCID: https://orcid.org/0000-0002-2926-7644)
- Estela Cordero-Laurent
- Elvira Segura‐Retana (ORCID: https://orcid.org/0000-0002-7281-4113)
- Romein Walters-Mais
- María Antonieta Jiménez-Pearson
- Roberto G. Melano (ORCID: https://orcid.org/0000-0002-0268-1028)
- Francisco Duarte-Martínez (ORCID: https://orcid.org/0000-0002-0280-0701)
- Tábata Elizondo-Alvarez
Institutions
- Toronto Public Health (CA)
- Ross University School of Veterinary Medicine (KN)
- Costa Rican Department of Social Security (CR)
- Instituto Costarricense de Investigación y Enseñanza en Nutrición y Salud (CR)
- Public Health Ontario (CA)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1016/j.jgar.2025.04.004
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00