Progression of Intracranial Hemorrhage Comparing Unfractionated Heparin versus Low Molecular Weight Heparin for Chemoprophylaxis in Traumatic Brain Injury
VTEp with LMWH in patients with TBI was associated with a lower risk of ICH progression, hospital LOS, and ICU LOS when compared to UFH. While cohort differences may have been contributory, LMWH remained independently associated with lower ICH progression and shorter LOS after adjusting for risk level and injury mechanism.
Authors
- Siviero Agazzi (ORCID: https://orcid.org/0000-0001-5760-0187)
- Kevin Salomon (ORCID: https://orcid.org/0000-0002-6541-7785)
- Emma J. Johnson (ORCID: https://orcid.org/0000-0003-1940-2280)
- Matthew Udine (ORCID: https://orcid.org/0000-0002-6114-0563)
- Jacob Wasserman (ORCID: https://orcid.org/0000-0003-0456-2142)
- Jennifer Glover (ORCID: https://orcid.org/0000-0002-8535-5198)
- Jay I. Kumar (ORCID: https://orcid.org/0000-0003-1552-5865)
- Sarah Cool
- Rahul Mhaskar
- Qian Luo (ORCID: https://orcid.org/0000-0002-3413-9727)
- Emily Weeden
- Abhinav Harish
- Kiran Kittur
- Grant Yatzkan
Institutions
- University of South Florida (US)
Publication Details
- Journal
- World Neurosurgery
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1016/j.wneu.2025.123982
- Citations
- 1
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 1.39