Potential impact of micro-196a2 and Toll-like receptor 2 gene polymorphisms on oral cancer prognosis and susceptibility

These findings suggest that miR-196a2 rs11614913 could play a stage-dependent role in RFS, influencing early-stage OSCC but losing prognostic significance in advanced disease. Additionally, TLR2 rs5743708 may contribute to the decreased OSCC risk.

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Publication Details

Journal
Archives of Oral Biology
Published
2025-04-14
DOI
https://doi.org/10.1016/j.archoralbio.2025.106271
Primary Topic
Immune Response and Inflammation
Type
article
Field-Weighted Citation Impact
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article

Potential impact of micro-196a2 and Toll-like receptor 2 gene polymorphisms on oral cancer prognosis and susceptibility

Gordana Šupić, Saša Jović, Marko Simonović, Dušan Mišić et al.
Archives of Oral Biology
Immune Response and Inflammation
article

Potential impact of micro-196a2 and Toll-like receptor 2 gene polymorphisms on oral cancer prognosis and susceptibility

Gordana Šupić, Saša Jović, Marko Simonović, Dušan Mišić, Aleksandra Petković Ćurčin, Marko Brkic, Ružica Kozomara, Srboljub Stošić, Dragan Pandzic
article en

Abstract

These findings suggest that miR-196a2 rs11614913 could play a stage-dependent role in RFS, influencing early-stage OSCC but losing prognostic significance in advanced disease. Additionally, TLR2 rs5743708 may contribute to the decreased OSCC risk.

Archives of Oral BiologyVol. 175
Military Medical Academy (RS), University clinical center of Republika Srpska (BA)
Good health and well-being
Openalex Percentile: Top 92%
Immune Response and Inflammation
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Potential impact of micro-196a2 and Toll-like receptor 2 gene polymorphisms on oral cancer prognosis and susceptibility — Gordana Šupić, Saša Jović, et al. · Archives of Oral Biology (2025) | TGRS Research Map | TGRS