Risk Factors Associated With Late-Onset Epilepsy in Dementia and Mild Cognitive Impairment
This study showed that the APOE4 allele, dementia onset before age 60 years, AD dementia subtype, worse cognition, stroke/TIA, and PD are associated with LOE development in PWCD. PWCD with these risk factors may be considered for routine screening with an electroencephalogram for early identification of LOE.
Authors
- Emily L. Johnson (ORCID: https://orcid.org/0000-0001-6457-938X)
- Ifrah Zawar (ORCID: https://orcid.org/0000-0002-6103-4250)
- Mark Quigg (ORCID: https://orcid.org/0000-0003-3035-9260)
- Carol A. Manning (ORCID: https://orcid.org/0000-0003-4205-2485)
- Jaideep Kapur (ORCID: https://orcid.org/0000-0002-8608-1352)
- Soutik Ghosal (ORCID: https://orcid.org/0000-0003-0548-3104)
Institutions
- University of Virginia (US)
Publication Details
- Journal
- JAMA Neurology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1001/jamaneurol.2025.0552
- Citations
- 10
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 14.71