A Narrowband 635 nm Autofluorescence Peak in Albino Mouse Eyes Found With Multi-Modal Imaging Reveals the Presence of Protoporphyrin IX in the Choroid
Our results reveal that substantial PPIX is present in the posterior tissues of albino (Balb/c) mouse eyes, and measurable with high-resolution spectral measurements, and suggest that the absence of the narrow band PPIX emission peaks in pigmented eyes arises at least in part from screening by RPE and choroidal melanin.
Authors
- Robert J. Zawadzki (ORCID: https://orcid.org/0000-0002-9574-156X)
- Edward N. Pugh (ORCID: https://orcid.org/0000-0002-3293-6538)
- Mayank Goswami (ORCID: https://orcid.org/0000-0001-8829-9980)
- Pengfei Zhang (ORCID: https://orcid.org/0000-0003-1628-4450)
- Suman K. Manna (ORCID: https://orcid.org/0000-0002-7632-8286)
Institutions
- Dalian University of Technology (CN)
- Dalian University (CN)
- University of California, Davis (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1167/iovs.66.4.29
- Citations
- 1
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- University of California, Davis