A Prospective Study Consortium for the Discovery and Validation of Early Detection Markers for Ovarian Cancer – Baseline Findings for CA125
Ongoing investigations in PREDICT are evaluating the early detection potential of tumor-associated autoantibodies and miRNAs using CA125 as a benchmark. PREDICT is a well-characterized resource for identifying and validating detection markers for EOC that may then be used in multimodal screening as a complement to CA125 and combined with imaging.
Authors
- Alpa V. Patel (ORCID: https://orcid.org/0000-0001-9997-1218)
- Lauren R. Teras (ORCID: https://orcid.org/0000-0003-2419-8536)
- Rudolf Kaaks (ORCID: https://orcid.org/0000-0003-3751-3929)
- Kathryn L. Terry (ORCID: https://orcid.org/0009-0002-5848-4661)
- Trasias Mukama (ORCID: https://orcid.org/0000-0002-6520-5272)
- Shelley S. Tworoger (ORCID: https://orcid.org/0000-0002-6986-7046)
- Giovanna Masala (ORCID: https://orcid.org/0000-0002-5758-9069)
- Renée T. Fortner (ORCID: https://orcid.org/0000-0002-1426-8505)
- Nicolas Wentzensen (ORCID: https://orcid.org/0000-0003-1251-0836)
- Holly Ruth Harris (ORCID: https://orcid.org/0000-0002-2572-6727)
- Hilde Langseth (ORCID: https://orcid.org/0000-0002-9446-4855)
- Naoko Sasamoto (ORCID: https://orcid.org/0000-0002-4526-2181)
- Marta Crous‐Bou (ORCID: https://orcid.org/0000-0003-1493-4288)
- Victoria Cooley
- Heljä‐Marja Surcel (ORCID: https://orcid.org/0000-0002-5770-1380)
Institutions
- Brigham and Women's Hospital (US)
- American Cancer Society (US)
- Harvard University (US)
- Oregon Health & Science University (US)
- German Cancer Research Center (DE)
- University of Washington (US)
- Heidelberg University (DE)
- Prevention Institute (US)
- Bellvitge University Hospital (ES)
- University Hospital Heidelberg (DE)
- Moffitt Cancer Center (US)
- Institut d'Investigació Biomédica de Bellvitge (ES)
- Fred Hutch Cancer Center (US)
- Institute of Cancer Research (CA)
- Borealis (Finland) (FI)
- Institut Català d'Oncologia (ES)
- Cancer Registry of Norway (NO)
- National Cancer Institute (US)
- Department of Health and Human Services (US)
- Imperial College London (GB)
- Oulu University of Applied Sciences (FI)
- Makerere University (UG)
- Heidelberg University (US)
- University of Oulu (FI)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-1845
- Citations
- 3
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.09
Funders
- U.S. Department of Defense
- U.S. Department of Health and Human Services
- World Health Organization
- Compagnia di San Paolo
- Universitetet i Tromsø
- Deutsches Krebsforschungszentrum
- Centre International de Recherche sur le Cancer
- Cancer Research UK
- National Institute for Health and Care Research
- Imperial College London
- European Commission
- Agence Nationale de la Recherche
- Institut National de la Santé et de la Recherche Médicale
- ZonMw
- Bundesministerium für Bildung und Forschung
- Cancerfonden
- Ministero della Salute
- Vetenskapsrådet
- Associazione Italiana per la Ricerca sul Cancro
- Deutsche Krebshilfe
- Institut Gustave-Roussy
- Mutuelle Générale de l'Education Nationale
- National Institutes of Health
- Centers for Disease Control and Prevention
- Medical Research Council
- World Cancer Research Fund
- Instituto de Salud Carlos III
- NIHR Imperial Biomedical Research Centre
- School of Public Health, Imperial College London
- National Heart, Lung, and Blood Institute
- National Cancer Institute