Neoadjuvant Chemotherapy and Surgery versus Surgery for Organ Preservation of T3 and T4a Nasal and Paranasal Sinus Squamous Cell Carcinoma: ECOG-ACRIN EA3163
These results support neoadjuvant chemotherapy as an effective intervention for SP in T3/T4a NPNSCC and deserve further evaluation.
Authors
- Ivan H. El‐Sayed (ORCID: https://orcid.org/0000-0001-8121-3726)
- Dong M. Shin (ORCID: https://orcid.org/0000-0002-8245-4174)
- Christopher H. Le (ORCID: https://orcid.org/0000-0002-7580-3030)
- Christine H. Chung (ORCID: https://orcid.org/0000-0001-5199-4306)
- Carl Henry Snyderman (ORCID: https://orcid.org/0000-0002-8920-4522)
- Barbara Ann Burtness (ORCID: https://orcid.org/0000-0003-4660-1859)
- Yael Flamand (ORCID: https://orcid.org/0000-0003-2150-6732)
- Nabil F. Saba (ORCID: https://orcid.org/0000-0003-4972-1477)
- C. Arturo Solares (ORCID: https://orcid.org/0000-0002-2794-5034)
- A. Bapsi Chakravarthy (ORCID: https://orcid.org/0000-0003-2824-2514)
- Rathan M. Subramaniam (ORCID: https://orcid.org/0000-0003-3973-4610)
- Fenghai Duan (ORCID: https://orcid.org/0000-0002-5084-0070)
- Paul Swiecicki (ORCID: https://orcid.org/0000-0003-2286-3555)
- Douglas R. Adkins (ORCID: https://orcid.org/0000-0003-3207-8227)
- Marc A. Cohen (ORCID: https://orcid.org/0000-0002-6104-7967)
- Maged Ghaly (ORCID: https://orcid.org/0000-0002-9007-3443)
- Stella Flampouri (ORCID: https://orcid.org/0000-0001-6489-5278)
- Ehab Y. Hanna (ORCID: https://orcid.org/0000-0003-3241-2440)
- Peter H. Hwang (ORCID: https://orcid.org/0000-0002-0786-4675)
- Chukwuemeka Ikpeazu (ORCID: https://orcid.org/0000-0003-4081-2719)
- Mark W. McDonald (ORCID: https://orcid.org/0000-0003-3021-9356)
- Saad A. Khan (ORCID: https://orcid.org/0000-0002-3440-9774)
- Michael A. Samuels (ORCID: https://orcid.org/0000-0002-6229-0184)
- Derrick T. Lin (ORCID: https://orcid.org/0009-0000-5022-3438)
- Rita Axelrod (ORCID: https://orcid.org/0009-0003-5740-0021)
Institutions
- Northwell Health (US)
- Cancer Prevention Institute of California (US)
- Memorial Sloan Kettering Cancer Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of Arizona (US)
- University of Miami (US)
- Thomas Jefferson University (US)
- Emory University (US)
- University of Pittsburgh (US)
- Palo Alto University (US)
- University of California, San Francisco (US)
- Washington University in St. Louis (US)
- University of Missouri–St. Louis (US)
- Brown University (US)
- University of Michigan (US)
- Thomas Jefferson University Hospital (US)
- The Mount (GB)
- Harvard University Press (US)
- Banner Health (US)
- Moffitt Cancer Center (US)
- Yale University (US)
- Kettering University (US)
- University of New Haven (US)
- Massachusetts General Hospital (US)
- ECOG-ACRIN Cancer Research Group (US)
- Piedmont Cancer Institute (US)
- Northwell Health Orthopaedic Institute (US)
- Dana-Farber Cancer Institute (US)
- Michigan Center for Translational Pathology (US)
- Michigan Cancer Research Consortium (US)
- Palo Alto Institute (US)
- UPMC Hillman Cancer Center (US)
- Jefferson Hospital (US)
- Sylvester Comprehensive Cancer Center (US)
- Dana-Farber Brigham Cancer Center (US)
- University of Arizona Cancer Center
- Stanford Cancer Institute
- University of Otago (NZ)
- Vanderbilt University Medical Center (US)
- The University of Notre Dame Australia (AU)
- Stanford University (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-4085
- Citations
- 3
- Primary Topic
- Head and Neck Surgical Oncology
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- American College of Radiology Imaging Network
- ECOG-ACRIN Cancer Research Group
- National Institutes of Health
- National Cancer Institute