Gastrodin enhances stress resilience through promoting Wnt/β-Catenin-dependent neurogenesis
These results suggested that GAS directly activates the Wnt/β-catenin signaling pathway, which promotes the proliferation and neuronal differentiation of NSPCs, thereby enhancing adult hippocampal neurogenesis and promoting stress resilience to mitigate the risk of depression.
Authors
- Zili You (ORCID: https://orcid.org/0000-0002-7776-6229)
- Yue Liu (ORCID: https://orcid.org/0000-0001-8042-1443)
- Meidan Wang (ORCID: https://orcid.org/0009-0000-6524-8881)
- Zhihuang Zhao
- Jinqiang Zhang (ORCID: https://orcid.org/0000-0003-1563-827X)
- Hui He (ORCID: https://orcid.org/0000-0003-1915-7756)
- Tao Zhou (ORCID: https://orcid.org/0000-0001-8508-9355)
- Yangyan Ge
- Pei Liu (ORCID: https://orcid.org/0009-0002-7331-4652)
- Chenghong Xiao
- Haili Zhang (ORCID: https://orcid.org/0000-0002-7839-4420)
Institutions
- Guiyang College of Traditional Chinese Medicine (CN)
- University of Electronic Science and Technology of China (CN)
- University of Freiburg (DE)
- Guizhou University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1016/j.jare.2025.04.017
- Citations
- 2
- Primary Topic
- Biological and pharmacological studies of plants
- Type
- article
- Field-Weighted Citation Impact
- 2.79