Enhancing Male Fertility Through Nutrition: The Role of L-Carnitine in Asthenozoospermic Patients
Infertility, which affects millions worldwide, often involves male factors such as asthenozoospermia, a condition marked by reduced sperm motility. While lifestyle and environmental factors are major contributors, nutritional interventions offer an effective, non-invasive approach to treatment. This case report examines the effects of L-carnitine supplementation on male infertility in a 37-year-old patient with a six-year history of primary infertility. The patient followed a three-month protocol that included 3000 mg of L-carnitine daily, dietary changes rich in antioxidants, and lifestyle modifications. Initial semen analysis revealed significant deficiencies, including progressive motility of 15% and a sperm count of 25 million/mL. After the intervention, notable improvements were observed: progressive motility increased to 50%, sperm count rose to 49 million/mL, and normal morphology improved from 3% to 7%. These results highlight the role of L-carnitine in supporting sperm mitochondrial function, reducing oxidative stress, and improving key fertility parameters. The findings are consistent with existing research demonstrating the potential of L-carnitine as a treatment for male infertility. This report underscores the value of individualized nutritional and supplementation strategies in enhancing reproductive health and suggests L-carnitine as a safe and effective option for treating asthenozoospermia.
Authors
- Akash More (ORCID: https://orcid.org/0000-0002-9958-1479)
- Namrata Anjankar
- Neha Nawale
- Nancy Nair
- Sanket Mahajan
- Jafar Shaikh
Institutions
- Datta Meghe Institute of Higher Education and Research (IN)
Publication Details
- Journal
- Journal of Pharmacy And Bioallied Sciences
- Published
- 2025-04-12
- DOI
- https://doi.org/10.4103/jpbs.jpbs_94_25
- Citations
- 1
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 1.70