Anti-TIGIT inhibitors plus PD-1 or PD-L1 inhibitors versus PD-1 or PD-L1 inhibitors for first-line treatment of advanced non-small cell lung cancer

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the effectiveness and safety of anti-TIGIT inhibitors in combination with PD-1 inhibitors or PD-L1 inhibitors compared to treatment with PD-1 inhibitors or PD-L1 inhibitors in the first-line treatment of advanced NSCLC. To assess the effectiveness and safety of anti-TIGIT inhibitors in combination with chemotherapy and PD-1 inhibitors or PD-L1 inhibitors compared to treatment with chemotherapy plus PD-1 inhibitors or PD-L1 inhibitors in the first-line treatment of advanced NSCLC.

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Publication Details

Journal
Cochrane Database of Systematic Reviews
Published
2025-04-14
DOI
https://doi.org/10.1002/14651858.cd015888
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

Anti-TIGIT inhibitors plus PD-1 or PD-L1 inhibitors versus PD-1 or PD-L1 inhibitors for first-line treatment of advanced non-small cell lung cancer

Jinhui Tian, Xiajing Chu, Ya Gao, Fanqi Wu et al.
12 links
Cochrane Database of Systematic Reviews
Lung Cancer Treatments and Mutations
article

Anti-TIGIT inhibitors plus PD-1 or PD-L1 inhibitors versus PD-1 or PD-L1 inhibitors for first-line treatment of advanced non-small cell lung cancer

Jinhui Tian, Xiajing Chu, Ya Gao, Fanqi Wu, Lun Li, Liang Yao, Ming Liu, Long Ge
article en

Abstract

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the effectiveness and safety of anti-TIGIT inhibitors in combination with PD-1 inhibitors or PD-L1 inhibitors compared to treatment with PD-1 inhibitors or PD-L1 inhibitors in the first-line treatment of advanced NSCLC. To assess the effectiveness and safety of anti-TIGIT inhibitors in combination with chemotherapy and PD-1 inhibitors or PD-L1 inhibitors compared to treatment with chemotherapy plus PD-1 inhibitors or PD-L1 inhibitors in the first-line treatment of advanced NSCLC.

Cochrane Database of Systematic ReviewsVol. 2025(5)
Central South University (CN), Shandong University (CN), Nanyang Technological University (SG), Lanzhou University Second Hospital (CN), Second Xiangya Hospital of Central South University (CN), Impact (CA), Lanzhou University (CN), McMaster University (CA)
Good health and well-being
Openalex Percentile: Top 88%
Lung Cancer Treatments and Mutations
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Anti-TIGIT inhibitors plus PD-1 or PD-L1 inhibitors versus PD-1 or PD-L1 inhibitors for first-line treatment of advanced non-small cell lung cancer — Jinhui Tian, Xiajing Chu, et al. · Cochrane Database of Systematic Reviews (2025) | TGRS Research Map | TGRS