Based on the Dual Pathway of Interaction-Mediated NF-κB in Cell Apoptosis and Immune Inflammation to Study the Effect of Danzhi Xiaoyao Powder on the Learning and Cognitive Ability of AD Model Rats
DXP can improve the learning and cognitive abilities of AD model rats, and its mechanism of action may be related to the regulation of the Akt/NF-κB apoptosis pathway mediated by NF-κB interaction and the p38MAPK/MK2/COX-2 immune inflammatory dual pathway.
Authors
- Zhipeng Meng (ORCID: https://orcid.org/0000-0001-9445-7981)
- Mingcheng Li (ORCID: https://orcid.org/0000-0003-2640-4305)
- Huping Wang (ORCID: https://orcid.org/0000-0002-9639-5355)
- Jiao Yang (ORCID: https://orcid.org/0000-0002-1553-5425)
- Yu-Jie Lyu
- Yun‐Yun Hu
- Jun Zhou (ORCID: https://orcid.org/0009-0005-1158-1167)
- Wenli Pei
- Yi-Qin Chen
- Yumei Han
Institutions
- Gansu University of Traditional Chinese Medicine (CN)
- Qujing Normal University (CN)
- Gansu Provincial Hospital of TCM (CN)
- Xiangyang Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Degenerative Neurological and Neuromuscular Disease
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/dnnd.s475290
- Primary Topic
- NF-κB Signaling Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00