[Effect of CMTM6 on PD-L1 in <i>Helicobacter pylori</i> infected gastric epithelial cells].
<i>Helicobacter pylori</i> infection up-regulates the expression level of CMTM6 in gastric mucosa cells, and CMTM6 can stabilize PD-L1 and maintain the protein level of PD-L1. <i>CMTM6</i> gene knockout may affect biological behaviors such as protein ubiquitination and cell surface receptor expression.
Authors
- Shigang Ding (ORCID: https://orcid.org/0000-0002-0831-0965)
- Wei Fu (ORCID: https://orcid.org/0000-0001-5248-7891)
- Jing Ning (ORCID: https://orcid.org/0000-0002-5454-3188)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-4460-045X)
- Wei‐Wei Fu (ORCID: https://orcid.org/0000-0001-7681-7015)
Institutions
- Peking University (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-18
- DOI
- https://doi.org/10.19723/j.issn.1671-167x.2025.02.004
- Primary Topic
- Chemokine receptors and signaling
- Type
- article