[Expression and regulatory mechanism of miR-34a in neonatal rat model of bron-chopulmonary dysplasia induced by hyperoxia].
The new BPD model of newborn SD rats can be successfully established by continuous exposure to 60% hyperoxia. The expression of miR-34a was up-regulated in the lung tissue of the new BPD model of neonatal rats. MiR-34a may play an important role in the occurrence and development of BPD by regulating Ang-1/Tie-2 signal pathway.
Authors
- Mengyue Huo
- Chunli Liu (ORCID: https://orcid.org/0000-0003-3671-2045)
- Yanbo Zhang (ORCID: https://orcid.org/0000-0003-1054-9657)
- Yuheng Zhang (ORCID: https://orcid.org/0000-0002-6785-0443)
- Hua Mei
Institutions
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-18
- DOI
- https://doi.org/10.19723/j.issn.1671-167x.2025.02.003
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article