Causal Links Between Corneal Biomechanics and Myopia: Evidence from Bidirectional Mendelian Randomization in the UK Biobank
This study establishes a causal relationship where reduced corneal biomechanics contribute to myopia, while myopia itself does not directly affect biomechanics. Corneal biomechanics could serve as a biomarker for assessing high myopia risk. These findings offer new insights into high myopia's pathological mechanisms and targeted prevention.
Authors
- Meixiao Shen (ORCID: https://orcid.org/0000-0002-4297-962X)
- Shenglong Luo
- Junjie Wang (ORCID: https://orcid.org/0000-0003-4708-9447)
- Hera Soha
- Xuefei Li (ORCID: https://orcid.org/0000-0001-6406-6461)
- Fan Lü (ORCID: https://orcid.org/0000-0003-0846-147X)
- Kuangching Lin
Institutions
- Wenzhou Medical University (CN)
- Affiliated Eye Hospital of Wenzhou Medical College (CN)
Publication Details
- Journal
- Bioengineering
- Published
- 2025-04-13
- DOI
- https://doi.org/10.3390/bioengineering12040412
- Citations
- 1
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province