An Atypical Case of Chronic Fungal Rhinosinusitis: Temporary Symptom Relief Resulted in a Delay of Diagnosis and Brain Abscess

A 67-year-old diabetic man with chronic invasive fungal rhinosinusitis (IFRS) experienced mild, remitting visual symptoms, delaying diagnosis. Despite early MRI evidence of orbital apex inflammation, spontaneous symptom resolution led to discontinuation of hospital visit. Eleven months later, he developed orbital apex syndrome and intracranial complications. Emergency surgery and antifungal therapy were initiated, but vision loss persisted. This case underscores the risk of transient symptom remission masking IFRS progression, emphasizing the importance of early intervention.

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Publication Details

Journal
Cureus
Published
2025-04-14
DOI
https://doi.org/10.7759/cureus.82226
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
0.00
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article

An Atypical Case of Chronic Fungal Rhinosinusitis: Temporary Symptom Relief Resulted in a Delay of Diagnosis and Brain Abscess

Arata Horii, Takeshi Takahashi, Ryota Kai, Tetsuhisa Hatase et al.
Cureus
Antifungal resistance and susceptibility
article

An Atypical Case of Chronic Fungal Rhinosinusitis: Temporary Symptom Relief Resulted in a Delay of Diagnosis and Brain Abscess

Arata Horii, Takeshi Takahashi, Ryota Kai, Tetsuhisa Hatase, Mio Yamamoto
article en

Abstract

A 67-year-old diabetic man with chronic invasive fungal rhinosinusitis (IFRS) experienced mild, remitting visual symptoms, delaying diagnosis. Despite early MRI evidence of orbital apex inflammation, spontaneous symptom resolution led to discontinuation of hospital visit. Eleven months later, he developed orbital apex syndrome and intracranial complications. Emergency surgery and antifungal therapy were initiated, but vision loss persisted. This case underscores the risk of transient symptom remission masking IFRS progression, emphasizing the importance of early intervention.

CureusVol. 17(4)
University of Niigata Prefecture (JP), Niigata University of Rehabilitation (JP), Niigata University (JP)
Openalex Percentile: Top 90%
Antifungal resistance and susceptibility
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