Geranylgeranylacetone as Prevention for Postoperative Atrial Fibrillation (GENIALITY)
The GENIALITY study aims to reduce PoAF incidence in the GGA group compared to the placebo group. Herewith, we expect to obtain proof of concept for a beneficial effect of GGA in preventing PoAF in patients undergoing cardiothoracic surgery. TRIAL REGISTRATION: Clinical Trial Information System (CTIS) registry: 2024-514743-28-00. Authorized on September 30th 2024.
Authors
- Etto C. Eringa (ORCID: https://orcid.org/0000-0002-9814-5149)
- Nimrat Grewal (ORCID: https://orcid.org/0000-0001-9981-8336)
- M. Louis Handoko (ORCID: https://orcid.org/0000-0002-8942-7865)
- Mellanie True Hills (ORCID: https://orcid.org/0000-0001-8298-4418)
- Bianca J.J.M. Brundel (ORCID: https://orcid.org/0000-0002-4768-234X)
- Natasja M.S. de Groot (ORCID: https://orcid.org/0000-0002-0259-6691)
- Kennedy S. Ramos (ORCID: https://orcid.org/0000-0002-0283-3765)
- Leonoor F.J. Wijdeveld
- Daniël H. van Raalte (ORCID: https://orcid.org/0000-0003-2894-6124)
- Robert J.M. Klautz (ORCID: https://orcid.org/0000-0002-6507-3855)
- Myrthe F. Kuipers (ORCID: https://orcid.org/0000-0002-6586-2213)
- Soufiane Nassiri (ORCID: https://orcid.org/0009-0004-2042-9469)
- Reinier L van der Palen
- Pieter Slijkerman
Institutions
- Leiden University Medical Center (NL)
- Erasmus MC (NL)
- Maastricht University (NL)
- Amsterdam Neuroscience (NL)
- Health Foundation (GB)
- Amsterdam University Medical Centers (NL)
- ReumaNederland (NL)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Cardiovascular Drugs and Therapy
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1007/s10557-025-07693-2
- Citations
- 4
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 5.44
Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek