Inflammation-Driven Prognosis in Advanced Heart Failure: A Machine Learning-Based Risk Prediction Model for One-Year Mortality

A successful ML-based prediction model was developed to accurately predict the one-year mortality risk in AdHF patients, with inflammation-driven factors being significant. The RF model integrating clinical features and inflammatory markers showed excellent performance and could assist clinical decision-making. Future research should conduct larger, multi-center, and prospective studies to further validate these findings.