Space–nonlocal description of cell movement

We propose a new space–nonlocal model based only on integral terms describing cell movement caused by various interactions. These terms retain the basic properties of the corresponding space–local (that is, differential) terms. Interactions between real objects take place at a certain distance between them, which may be caused, for example, by their geometric shapes. Unlike the local (differential) model, the proposed space–nonlocal model does not exhibit blow–ups of solutions. On the other hand, the nonlocal terms approximate the corresponding local terms. The model refers to cancer invasion on surrounding tissue, but the generalization to any movement of biological object is straightforward. The performed numerical simulations show how nonlocal effects affect the dynamics of the system under consideration.

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Publication Details

Journal
Discrete and Continuous Dynamical Systems - B
Published
2025-01-01
DOI
https://doi.org/10.3934/dcdsb.2025058
Primary Topic
Mathematical Biology Tumor Growth
Type
article
Field-Weighted Citation Impact
0.00

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article

Space–nonlocal description of cell movement

Milena Matusik, Krzysztof Topolski, Mirosław Lachowicz
Discrete and Continuous Dynamical Systems - B
Mathematical Biology Tumor Growth
article

Space–nonlocal description of cell movement

Milena Matusik, Krzysztof Topolski, Mirosław Lachowicz
article en

Abstract

We propose a new space–nonlocal model based only on integral terms describing cell movement caused by various interactions. These terms retain the basic properties of the corresponding space–local (that is, differential) terms. Interactions between real objects take place at a certain distance between them, which may be caused, for example, by their geometric shapes. Unlike the local (differential) model, the proposed space–nonlocal model does not exhibit blow–ups of solutions. On the other hand, the nonlocal terms approximate the corresponding local terms. The model refers to cancer invasion on surrounding tissue, but the generalization to any movement of biological object is straightforward. The performed numerical simulations show how nonlocal effects affect the dynamics of the system under consideration.

Discrete and Continuous Dynamical Systems - BVol. 30(11)
Polish Naval Academy (PL), University of Gdańsk (PL), Institute of Mathematics (PL)
Uniwersytet Warszawski
Reduced inequalities
Openalex Percentile: Top 91%
Mathematical Biology Tumor Growth
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Space–nonlocal description of cell movement — Milena Matusik, Krzysztof Topolski, et al. · Discrete and Continuous Dynamical Systems - B (2025) | TGRS Research Map | TGRS