Evaluation of Total Thyroidectomy with Prophylactic Central Neck Dissection as an Alternative to Total Thyroidectomy Alone in Clinically Node-Negative Papillary Thyroid Carcinoma

Background: PTC is the most popular form of differentiated thyroid carcinoma. Total thyroidectomy is the preferredprocedure for all PTC. In spite of CND is performed for clinically nodal-positive patients, it still controversial incases with clinically negative nodes.Aim of work: The purpose of this study is to compare the incidence of recurrence and complications of TT onlywith TT plus pCND in patients with clinically negative L.N and PTC.Patients and methods: This retrospective study was conducted in the General Surgery Department at AinShams University Hospitals. The study involved 40 diagnosed cases of PTC with clinically node-negative disease,all of which were operated on between January 2021 and January 2023.Results: The incidence of complications was similar in both groups. The rate of temporary recurrent laryngealnerve injury was 5% in both groups. The rate of transient hypocalcemia was 5% in the TT only group and 10% inthe TT with pCND group. Additionally, the rate of permanent hypocalcemia was 0% in the TT only group, while itwas 5% in the TT with pCND group. pCND does not significantly reduce the local recurrence risk in cases of PTC.Conclusion: Total thyroidectomy with pCND in clinically node-negative disease was not associated with increasein postoperative complications, in spite of having a longer operation time compared to total thyroidectomy withoutpCND. However, 40% of cases who performed total thyroidectomy with pCND were found to have lymph nodemetastasis.

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Journal
Ain Shams Journal of Surgery
Published
2025-04-01
DOI
https://doi.org/10.21608/asjs.2025.349526.1176
Primary Topic
Thyroid Cancer Diagnosis and Treatment
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article
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article

Evaluation of Total Thyroidectomy with Prophylactic Central Neck Dissection as an Alternative to Total Thyroidectomy Alone in Clinically Node-Negative Papillary Thyroid Carcinoma

Ahmed Saeed Saad, Dina Mohamed Hanafy, Yasmine Hany Abdel Moamen El Zohery
Ain Shams Journal of Surgery
Thyroid Cancer Diagnosis and Treatment
article

Evaluation of Total Thyroidectomy with Prophylactic Central Neck Dissection as an Alternative to Total Thyroidectomy Alone in Clinically Node-Negative Papillary Thyroid Carcinoma

Ahmed Saeed Saad, Dina Mohamed Hanafy, Yasmine Hany Abdel Moamen El Zohery
article en

Abstract

Background: PTC is the most popular form of differentiated thyroid carcinoma. Total thyroidectomy is the preferredprocedure for all PTC. In spite of CND is performed for clinically nodal-positive patients, it still controversial incases with clinically negative nodes.Aim of work: The purpose of this study is to compare the incidence of recurrence and complications of TT onlywith TT plus pCND in patients with clinically negative L.N and PTC.Patients and methods: This retrospective study was conducted in the General Surgery Department at AinShams University Hospitals. The study involved 40 diagnosed cases of PTC with clinically node-negative disease,all of which were operated on between January 2021 and January 2023.Results: The incidence of complications was similar in both groups. The rate of temporary recurrent laryngealnerve injury was 5% in both groups. The rate of transient hypocalcemia was 5% in the TT only group and 10% inthe TT with pCND group. Additionally, the rate of permanent hypocalcemia was 0% in the TT only group, while itwas 5% in the TT with pCND group. pCND does not significantly reduce the local recurrence risk in cases of PTC.Conclusion: Total thyroidectomy with pCND in clinically node-negative disease was not associated with increasein postoperative complications, in spite of having a longer operation time compared to total thyroidectomy withoutpCND. However, 40% of cases who performed total thyroidectomy with pCND were found to have lymph nodemetastasis.

Ain Shams Journal of SurgeryVol. 18(2)
Ain Shams University (EG)
Good health and well-being
Openalex Percentile: Top 90%
Thyroid Cancer Diagnosis and Treatment
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Evaluation of Total Thyroidectomy with Prophylactic Central Neck Dissection as an Alternative to Total Thyroidectomy Alone in Clinically Node-Negative Papillary Thyroid Carcinoma — Ahmed Saeed Saad, Dina Mohamed Hanafy, et al. · Ain Shams Journal of Surgery (2025) | TGRS Research Map | TGRS