Aripiprazole alleviates the high prolactin levels induced by amisulpride via distinct molecular mechanisms: a network pharmacology and molecular docking study
These findings highlight the distinct signaling pathways and molecular networks involved in prolactin regulation by aripiprazole and amisulpride and provide new insights into the mechanisms of these drugs in schizophrenia treatment. Further pharmacological and clinical research is needed to validate the complex regulatory networks and in vivo effects.
Authors
- Kaifang Yao (ORCID: https://orcid.org/0000-0002-4142-1835)
- Chuanjun Zhuo (ORCID: https://orcid.org/0000-0002-3793-550X)
- Lei Yang (ORCID: https://orcid.org/0000-0002-2956-0920)
- Chao Li (ORCID: https://orcid.org/0000-0002-0240-5170)
- Qiuyu Zhang (ORCID: https://orcid.org/0000-0002-4823-5031)
- Hongjun Tian (ORCID: https://orcid.org/0000-0002-3919-3749)
Institutions
- Tianjin Anding Hospital (CN)
- Tianjin Fourth Hospital (CN)
Publication Details
- Journal
- BMC Psychiatry
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1186/s12888-025-06818-z
- Citations
- 1
- Primary Topic
- Retinoids in leukemia and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China