Diagnostic Value of Left Atrial Strain Quantified by CMR-FT in Hypertensive Patients with Ischemic Stroke

目的：探讨在高血压患者中心脏磁共振特征跟踪技术(CMR-FT)量化的左心房(LA)应变与缺血性脑卒中(IS)的关系。方法：100例高血压患者据颅脑磁共振检查结果分为无-IS组62例和IS组38例，比较两组患者年龄、性别、身体质量指数(BMI)等一般资料和左心室、左心房心脏磁共振(CMR)功能参数。Logistic回归分析高血压合并IS的影响因素，受试者工作特征(ROC)曲线分析各指标的预测效能。结果：IS组年龄、同型半胱氨酸(Hcy)、LA最小容积(LA Vmin)高于无-IS组(P Objective: To investigate the relationship between left atrial (LA) strain quantified by cardiac magnetic resonance feature tracking (CMR-FT) and ischemic stroke (IS) in hypertensive patients. Methods: 100 hypertensive patients were divided into a non-IS group of 62 cases and an IS group of 38 cases based on the results of cranial magnetic resonance imaging. General data such as age, gender, and body mass index (BMI), as well as cardiac magnetic resonance (CMR) functional parameters of the left ventricle and left atrium, were compared between the two groups. Logistic regression analysis was used to identify factors influencing IS in hypertensive patients, and receiver operating characteristic (ROC) curve analysis was performed to evaluate the predictive efficacy of each index. Results: The IS group had higher age, homocysteine (Hcy), and minimum left atrial volume (LA Vmin) compared to the non-IS group (P < 0.05), while strain, strain rate, and ejection fraction during the reservoir, pump, and conduit phases were lower than in the non-IS group (P < 0.05). Age, Hcy, and reservoir phase strain were independent risk factors for IS in hypertensive patients. In single-index analysis, reservoir phase strain had higher sensitivity, while Hcy had the highest diagnostic specificity; in combined detection, the comprehensive efficacy was higher. Conclusion: Age, Hcy, reservoir phase strain, and their combined indicators have certain diagnostic value for hypertensive patients with IS and can optimize treatment and management for these patients.