Advanced imaging characterization of post-chemoradiation glioblastoma stratified by diffusion MRI phenotypes known to predict favorable anti-VEGF response
Post-chemoradiation glioblastomas with a diffusion MRI phenotype that is known to predict a favorable response to anti-VEGF (ADC<sub>L</sub> ≥1240 µm<sup>2</sup>/s) have distinct biological features, with different perfusion and metabolic characteristics, and T<sub>2</sub> relaxation times.
Authors
- David A. Nathanson (ORCID: https://orcid.org/0000-0002-4919-9159)
- Robert Michael Prins (ORCID: https://orcid.org/0000-0002-6282-6583)
- Noriko Salamon (ORCID: https://orcid.org/0000-0002-3520-9467)
- Richard G. Everson (ORCID: https://orcid.org/0000-0003-2809-3061)
- Benjamin M. Ellingson (ORCID: https://orcid.org/0000-0002-2764-6640)
- Jingwen Yao (ORCID: https://orcid.org/0000-0002-8828-1841)
- Phioanh Leia Nghiemphu (ORCID: https://orcid.org/0000-0003-4064-6079)
- Francesco Sanvito (ORCID: https://orcid.org/0000-0003-3379-9958)
- Albert Lai (ORCID: https://orcid.org/0000-0002-7265-2986)
- Timothy F. Cloughesy (ORCID: https://orcid.org/0000-0002-8656-7483)
- Linda M. Liau (ORCID: https://orcid.org/0000-0002-4053-0052)
- Blaine S.C. Eldred (ORCID: https://orcid.org/0000-0002-3351-3895)
- Catalina Raymond (ORCID: https://orcid.org/0000-0003-2757-439X)
- Kunal Patel (ORCID: https://orcid.org/0000-0002-9854-9178)
- Ashley Teraishi (ORCID: https://orcid.org/0009-0004-3442-8109)
- John Gao
- Cole Miller
- Irina Kryukov
Institutions
- University of California, Los Angeles (US)
Publication Details
- Journal
- Journal of Neuro-Oncology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1007/s11060-025-05019-8
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Defense
- Break Through Cancer
- Cure Brain Cancer Foundation
- National Institutes of Health
- National Cancer Institute