Which Is the Best Option for <scp>AxSpA</scp> Patients After First <scp>TNFi</scp> Failure: Switch to Secukinumab or Cycling With Other <scp>TNFi</scp> ?

In axSpA exposed to a TNFi, switching to a second TNFi has comparable effectiveness to switching to SEC. SEC may be a better option in patients who experienced primary failure of TNFi, whereas an alternative TNFi may be preferred in patients with higher CRP levels or Achilles enthesitis, or who are currently smoking.

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Publication Details

Journal
International Journal of Rheumatic Diseases
Published
2025-04-01
DOI
https://doi.org/10.1111/1756-185x.70212
Citations
1
Primary Topic
Spondyloarthritis Studies and Treatments
Type
article
Field-Weighted Citation Impact
1.67
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article

Which Is the Best Option for AxSpA Patients After First TNFi Failure: Switch to Secukinumab or Cycling With Other TNFi ?

Özlem Kılıç, Mehmet Nur Kaya, Duygu Tecer, Sedat Yılmaz
1 citations
International Journal of Rheumatic Diseases
Spondyloarthritis Studies and Treatments
1.67
article

Which Is the Best Option for AxSpA Patients After First TNFi Failure: Switch to Secukinumab or Cycling With Other TNFi ?

Özlem Kılıç, Mehmet Nur Kaya, Duygu Tecer, Sedat Yılmaz
article en
1 citations

Abstract

In axSpA exposed to a TNFi, switching to a second TNFi has comparable effectiveness to switching to SEC. SEC may be a better option in patients who experienced primary failure of TNFi, whereas an alternative TNFi may be preferred in patients with higher CRP levels or Achilles enthesitis, or who are currently smoking.

International Journal of Rheumatic DiseasesVol. 28(4)
Sağlık Bilimleri Üniversitesi (TR)
Good health and well-being
Openalex Percentile: Top 18%
Spondyloarthritis Studies and Treatments
1.67
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