Occurrence, Risk Factors, and Prognosis of Acute Cerebral Microinfarcts in <scp>CADASIL</scp>
ACMIs were not rare in patients with CADASIL. PFO could independently predict the risk of ACMIs in CADASIL. Furthermore, the majority of ACMIs can disappear at 1 year of follow-up. The findings indicate that ACMIs, influenced by PFO, are prevalent in CADASIL and associated with a decline in quality of life and functional outcomes over time.
Authors
- Zhuoxin Guo
- Bingjun Zhang (ORCID: https://orcid.org/0000-0002-9641-2485)
- Aimin Wu (ORCID: https://orcid.org/0000-0001-5889-4885)
- Rong Cai (ORCID: https://orcid.org/0000-0001-6793-5765)
- Zhengqi Lu
- Xuejiao Men
- Bin Qin (ORCID: https://orcid.org/0000-0001-8244-127X)
- Hengfang Ruan (ORCID: https://orcid.org/0000-0002-7690-9400)
- Haiyan Li (ORCID: https://orcid.org/0000-0002-0290-4076)
- Hui Li (ORCID: https://orcid.org/0000-0002-4114-8349)
- Lei Wei (ORCID: https://orcid.org/0000-0001-5140-0504)
- Yongqiang Dai
Institutions
- Sun Yat-sen University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Annals of Clinical and Translational Neurology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1002/acn3.70054
- Citations
- 1
- Primary Topic
- Cerebrovascular and genetic disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China
- Guangdong Medical Research Foundation