NRF2 Antioxidant Cellular System as a Therapeutic Target for Enhancing Cancer Radiosensitivity

Contents 1. Introduction 2. Molecular mechanisms of the cellular NRF2 antioxidant system function 3. Activation of the NRF2 antioxidant system in cancer cells under oxidative stress caused by ionizing irradiation 4. Activation of NRF2 as a factor of radioresistance 5. NRF2 antioxidant system of the cell as a target of targeted therapy to increase radiosensitivity of cancer cells 6. Conclusion

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Publication Details

Journal
Meditsinskaya Fizika
Published
2025-04-14
DOI
https://doi.org/10.52775/1810-200x-2025-105-1-94-109
Primary Topic
Genomics, phytochemicals, and oxidative stress
Type
article
Field-Weighted Citation Impact
0.00
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NRF2 Antioxidant Cellular System as a Therapeutic Target for Enhancing Cancer Radiosensitivity

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NRF2 Antioxidant Cellular System as a Therapeutic Target for Enhancing Cancer Radiosensitivity

K. V. Tikunova, Yves De Deene, Alexey Goltsov, G. G. Golyshev, O. A. Zaytsev
article en

Abstract

Contents 1. Introduction 2. Molecular mechanisms of the cellular NRF2 antioxidant system function 3. Activation of the NRF2 antioxidant system in cancer cells under oxidative stress caused by ionizing irradiation 4. Activation of NRF2 as a factor of radioresistance 5. NRF2 antioxidant system of the cell as a target of targeted therapy to increase radiosensitivity of cancer cells 6. Conclusion

Meditsinskaya Fizika(1)
MIREA - Russian Technological University (RU), Federal University Dutse
Openalex Percentile: Top 93%
Genomics, phytochemicals, and oxidative stress
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