Genomic characterization of plasmids of mcr-1-positive Escherichia coli isolated from cohabiting rats, dairy cattle and pigs
E. coli isolates from cohabiting rats and pigs were genetically distinct, but one pair of isolates had very similar IncX4 plasmids, suggesting the potential for horizontal spread of plasmids carrying mcr genes. These findings suggest a threat of resistant E. coli spreading between cohabiting animals and into the environment. This underscores the importance of conducting integrated One-Health studies.
Authors
- Natalia A. Casanova (ORCID: https://orcid.org/0000-0001-8807-4618)
- Alejandra Corso (ORCID: https://orcid.org/0000-0003-1183-6746)
- Diego Faccone (ORCID: https://orcid.org/0009-0000-2688-8229)
- Christine Seah
- Regino Cavia (ORCID: https://orcid.org/0000-0003-3460-6644)
- Johana E. Dominguez (ORCID: https://orcid.org/0000-0002-5705-9834)
- Rosario Lovera (ORCID: https://orcid.org/0000-0002-7838-2243)
- Florencia Martino (ORCID: https://orcid.org/0009-0006-1381-6326)
- Mariano E. Fernández-Miyakawa (ORCID: https://orcid.org/0000-0001-5251-4685)
- Roberto G. Melano (ORCID: https://orcid.org/0000-0002-0268-1028)
Institutions
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- National Institute of Industrial Technology (AR)
- Administración Nacional de Laboratorios e Institutos de Salud (AR)
- Public Health Ontario (CA)
- Fundación Ciencias Exactas y Naturales (AR)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1186/s12917-025-04665-4
- Citations
- 2
- Primary Topic
- Escherichia coli research studies
- Type
- article
- Field-Weighted Citation Impact
- 3.60
Funders
- Instituto Nacional de Tecnología Agropecuaria