Emergence and characterization of mixed Candida auris strain infections in China
Comparative analyses revealed notable differences in biofilm formation, environmental survival, and secretion of virulence factors between the co-colonizing or co-infecting strains of C. auris. These biological and genetic disparities may present significant challenges for the diagnosis and treatment of C. auris infections, as strains with different genetic backgrounds may exhibit varying abilities to colonize host or environmental niches.
Authors
- Haiqing Chu (ORCID: https://orcid.org/0000-0002-9168-7295)
- Zhangyue Guan
- Jian Bing (ORCID: https://orcid.org/0000-0003-1212-1806)
- Han Du (ORCID: https://orcid.org/0000-0002-8488-6755)
- Guanghua Huang (ORCID: https://orcid.org/0000-0002-4761-7548)
- Yan‐Feng Huang
- Weihong Liang (ORCID: https://orcid.org/0000-0002-1143-6681)
- Penghao Guo (ORCID: https://orcid.org/0000-0002-9473-7649)
- Tianhong Zheng
Institutions
- Tongji University (CN)
- Sun Yat-sen University (CN)
- Fudan University (CN)
- Shanghai Pulmonary Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Infection
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1007/s15010-025-02536-6
- Citations
- 3
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 4.19
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China