Identification of a potential miRNA–mRNA regulatory network for ischemic stroke by using bioinformatics methods: a retrospective study based on the Gene Expression Omnibus database
This study identifies a novel miRNA-mRNA regulatory network in IS, offering potential biomarkers for diagnosis and targets for therapeutic intervention. Our findings bridge the gap between clinical observations and molecular mechanisms, paving the way for improved IS management.
Authors
- Guo-Ming Chen (ORCID: https://orcid.org/0000-0002-2629-5420)
- Chengcheng Ji (ORCID: https://orcid.org/0000-0003-3235-0921)
- Jiyuan Zheng (ORCID: https://orcid.org/0000-0003-3735-1309)
- Xiangjun Qi (ORCID: https://orcid.org/0000-0003-1616-5400)
- Weinv Fan
- Yulan Jin (ORCID: https://orcid.org/0000-0002-9716-1948)
- Na He (ORCID: https://orcid.org/0000-0002-9712-7782)
- Nan Zhong (ORCID: https://orcid.org/0009-0001-0173-6584)
- Xiaodan Zhang (ORCID: https://orcid.org/0000-0002-7809-8496)
- Zhaoying Chen (ORCID: https://orcid.org/0000-0002-2231-7135)
- Yu Hu (ORCID: https://orcid.org/0000-0003-3883-3887)
- Bohui Zheng
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Shaoxing University (CN)
- Ningbo No. 2 Hospital (CN)
- Ningbo No.6 Hospital (CN)
- University of Hong Kong (HK)
- University of Edinburgh (GB)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.3389/fimmu.2025.1467865
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87