The 50% effective dose of remimazolam combined with different doses of esketamine for painless gastroscopy
The ED50 of remimazolam combined with 0 mg/kg, 0.2 mg/kg, and 0.4 mg/kg of esketamine for induction of anaesthesia during painless gastroscopy was 0.344 mg/kg, 0.289 mg/kg, and 0.193 mg/kg, respectively. Combining esketamine with remimazolam for induction of anaesthesia during painless gastroscopy offers advantages in terms of haemodynamic stability and reduced adverse effects.
Authors
- Yiping Guo (ORCID: https://orcid.org/0009-0008-0497-9363)
- Longyi Zhang (ORCID: https://orcid.org/0000-0003-3625-489X)
- Linji Li
- Linlin Chen (ORCID: https://orcid.org/0000-0001-7618-4385)
- Xianchun Liu
- Wei Mao (ORCID: https://orcid.org/0000-0003-1253-5670)
- Li Zhao (ORCID: https://orcid.org/0000-0002-6297-528X)
- Ying Xie (ORCID: https://orcid.org/0000-0001-8226-4242)
- Xuelei Zhou (ORCID: https://orcid.org/0009-0006-2261-2456)
Institutions
- North Sichuan Medical University (CN)
Publication Details
- Journal
- Scientific Reports
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1038/s41598-025-97649-1
- Citations
- 4
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 8.76