Examination of the functions and mechanism of KCP in mediating paclitaxel resistance in cervical squamous carcinoma cells
<i>KCP</i> increased resistance of cervical cancer to paclitaxel by enhancing cell proliferation and colony formation. We observed that <i>KCP</i> could act positively on the downstream gene <i>SERPINB3</i> and negatively on the downstream gene <i>CEBPA</i> to affect the resistance of cervical carcinoma cells to paclitaxel.
Authors
- Jianqing Xu (ORCID: https://orcid.org/0000-0003-0896-9273)
- Yun-Fan Wang
- Ji Chen
- Jingjing Zhang (ORCID: https://orcid.org/0000-0002-6948-1813)
- Z. Liu
- Ming Wang (ORCID: https://orcid.org/0000-0002-4628-8826)
- Yan Wang (ORCID: https://orcid.org/0000-0001-5960-3576)
- Yang Liu (ORCID: https://orcid.org/0000-0002-4161-7643)
- Yumei Wu (ORCID: https://orcid.org/0000-0002-2242-9348)
- Yue He (ORCID: https://orcid.org/0000-0003-4041-9271)
Institutions
- Capital Medical University (CN)
- Beijing Obstetrics and Gynecology Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.3389/fonc.2025.1550032
- Citations
- 2
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 1.61