5-methoxytryptophan ameliorates renal ischemia/reperfusion injury by alleviating endoplasmic reticulum stress-mediated apoptosis through the Nrf2/HO-1 pathway
Our findings suggest that 5-MTP alleviates renal I/R injury by inhibiting ERS-related apoptosis via the Nrf2/HO-1 pathway.
Authors
- Xiangkun Li
- Shaona Li
- Bing Zhang (ORCID: https://orcid.org/0000-0001-8556-8049)
- Hongjuan Yang (ORCID: https://orcid.org/0009-0002-1234-3636)
- Lingyu Li (ORCID: https://orcid.org/0000-0001-8191-0521)
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-14
- DOI
- https://doi.org/10.3389/fphar.2025.1506482
- Citations
- 1
- Primary Topic
- Heme Oxygenase-1 and Carbon Monoxide
- Type
- article
- Field-Weighted Citation Impact
- 0.81