Polyvinylidene Fluoride/Eucalyptus Oil <i>Citriodora</i> Wound Dressing Containing Piezoelectric β Phase

ABSTRACT Polyvinylidene fluoride (PVDF) /Eucalyptus oil Citriodora wound dressing containing piezoelectric β phase was fabricated by solution casting method. The measurement of water contact angle, moisture content (MC), thickness, density, opacity, swelling degree, water vapor transmission rate (WVTR), color parameters, and mechanical properties, and also the tests of physical appearance, attenuated total reflection–Fourier transform infrared (ATR–FTIR), scanning electron microscopy (SEM), antibacterial activity, and cytotoxicity were conducted for the investigation of prepared wound dressing features and performance. Based on the results, the contact angle of pure PVDF film was obtained as 123.5° while it was measured as 86.7° for the wound dressing. Furthermore, the MC parameter for pure PVDF and wound dressing films was achieved as 16.66% and 18.75%, respectively. The values of the inhibition zone for the wound dressing against Staphylococcus aureus ( S. aureus ) and Escherichia coli ( E. coli ) were obtained as 33.56 and 31.08 mm, respectively. Moreover, the wound dressing exhibited a 117% cell viability after 72 h, in contrast to the pure PVDF sample which only achieved a 26% cell viability.