Identification of mitochondrial function and programmed cell death associated key biomarkers and the circRNA-miRNA-mRNA regulatory network in systemic lupus erythematosus
Our study ultimately identified two biomarkers (IFI27 and LAMP3) related to mitochondrial function and programmed cell death that play an important role in SLE. In the future, IFI27 and LAMP3 have the potential to become important biomarkers in the diagnosis and treatment of SLE. Their role in the immune response may provide new strategies for the treatment of SLE.
Authors
- Hui Zhou
- Junjie Cao
- Aifang Li (ORCID: https://orcid.org/0000-0003-4036-9841)
- Gan Luo (ORCID: https://orcid.org/0000-0002-3644-5752)
- Yujie Yan (ORCID: https://orcid.org/0000-0002-9455-8106)
Institutions
- Xi'an Medical University (CN)
- Xi'an Peihua University (CN)
- The Eighth Hospital of Xi'an (CN)
- Xi'an Chest Hospital (CN)
- First Hospital of Xi'an (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-04-14
- DOI
- https://doi.org/10.3389/fmolb.2025.1586294
- Citations
- 1
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.81