Loss of chromosome Y is unrelated to the composition of the tumor microenvironment and patient prognosis in muscle-invasive urothelial bladder cancers
The lack of a clear association of LOY with histopathological parameters of cancer aggressiveness, patient prognosis, and parameters describing the tumor microenvironment strongly argues against the driving role of LOY in bladder cancer progression and cancer-associated immune reactions.
Authors
- Niclas C. Blessin (ORCID: https://orcid.org/0000-0001-8043-3081)
- Maximilian Lennartz (ORCID: https://orcid.org/0000-0002-1572-8200)
- Guido Sauter (ORCID: https://orcid.org/0000-0002-9024-4978)
- Krystian Kaczmarek (ORCID: https://orcid.org/0000-0002-4898-960X)
- Tobias Klatte (ORCID: https://orcid.org/0000-0002-4392-6861)
- Henrik Samtleben
- Annika Fendler (ORCID: https://orcid.org/0000-0002-7267-0981)
- Nico Adamini
- Sebastian Hofbauer (ORCID: https://orcid.org/0000-0002-1796-9905)
- Michael Rink
- Sarah Weinberger (ORCID: https://orcid.org/0000-0002-4259-8990)
- Joachim Weischenfeldt (ORCID: https://orcid.org/0000-0002-3917-5524)
- Kira Furlano (ORCID: https://orcid.org/0000-0003-1724-7061)
- Simon Schallenberg (ORCID: https://orcid.org/0000-0002-7897-7116)
- Sarah Jane Pauline Minner (ORCID: https://orcid.org/0000-0003-0765-3568)
- Sefer Elezkurtaj (ORCID: https://orcid.org/0000-0002-1699-1270)
- David Horst (ORCID: https://orcid.org/0000-0003-4755-5743)
- Marcin Słojewski (ORCID: https://orcid.org/0000-0003-3679-7325)
- Thorsten Ecke (ORCID: https://orcid.org/0000-0002-0787-2763)
- Henning Plage (ORCID: https://orcid.org/0000-0002-7680-1870)
- Henrik Zecha
- Florian Roßner (ORCID: https://orcid.org/0000-0003-1763-765X)
- Ronald Simon (ORCID: https://orcid.org/0000-0003-0158-4258)
- Martina Kluth (ORCID: https://orcid.org/0000-0003-4782-4616)
- Viktoria Ahlburg
- Andreas Holger Marx (ORCID: https://orcid.org/0000-0002-5182-8364)
- Stefan Koch (ORCID: https://orcid.org/0000-0001-6606-6369)
- Margit Fisch
- Thorsten Schlomm
Institutions
- University of Copenhagen (DK)
- Universität Hamburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- St. Marien Hospital (DE)
- Helios Hospital Bad Saarow (DE)
- Albertinen Diakoniewerk (DE)
- Klinikum Fulda (DE)
- Pomeranian Medical University (PL)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1186/s12885-025-14019-w
- Citations
- 2
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.01