Prediction and Prognostic Role of Left Ventricular Systolic Dysfunction in Family Screening for Dilated Cardiomyopathy and Non-Dilated Left Ventricular Cardiomyopathy
Relatives of DCM/NDLVC probands who developed LV systolic dysfunction during a long follow-up had a significant increased risk of major adverse cardiovascular outcomes. However, LV systolic dysfunction detected by FSP showed a better prognosis. In this context, genetics, Holter ECG and LV-GLS demonstrated their functional role for disease and event prediction.
Authors
- Stefania Lenarduzzi (ORCID: https://orcid.org/0000-0001-8450-1694)
- Alessandro Folgheraiter
- Marta Gigli (ORCID: https://orcid.org/0000-0002-3856-937X)
- Gianfranco Sinagra (ORCID: https://orcid.org/0000-0003-2700-8478)
- Giorgia Girotto (ORCID: https://orcid.org/0000-0003-4507-6589)
- Carola Pio Loco Detto Gava (ORCID: https://orcid.org/0000-0003-2690-5169)
- Martina Setti (ORCID: https://orcid.org/0000-0002-3618-2833)
- Ilaria Gandin (ORCID: https://orcid.org/0000-0003-3196-2491)
- Jacopo Giulio Rizzi (ORCID: https://orcid.org/0009-0007-5511-9147)
- Matteo Dal Ferro (ORCID: https://orcid.org/0000-0002-2310-0448)
- Davide Stolfo (ORCID: https://orcid.org/0000-0002-4538-6811)
- Luisa Mestroni (ORCID: https://orcid.org/0000-0003-1116-2286)
- Beatrice Spedicati (ORCID: https://orcid.org/0000-0002-7432-4708)
- Eva Del Mestre (ORCID: https://orcid.org/0009-0001-5432-9288)
- Marco Merlo
- Giovanni Maria Severini (ORCID: https://orcid.org/0000-0002-5790-2000)
- Renata Korcova (ORCID: https://orcid.org/0009-0005-9890-4343)
- Alessia Paldino (ORCID: https://orcid.org/0000-0002-5823-3777)
Institutions
- University of Verona (IT)
- University of Trieste (IT)
- IRCCS Materno Infantile Burlo Garofolo (IT)
- ERN GUARD-Heart (NL)
- Azienda Sanitaria Universitaria Integrata di Trieste (IT)
- University of Colorado Anschutz Medical Campus (US)
Publication Details
- Journal
- European Journal of Heart Failure
- Published
- 2025-04-13
- DOI
- https://doi.org/10.1002/ejhf.3657
- Citations
- 1
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.39