Role of Serum Brain‐Derived Neurotrophic Factor as a Biomarker of Chronic Pain in Older Adults
Our study is the first to reveal that the relationship between serum BDNF and chronic pain is distinctly modulated by sex and depression. This novel insight challenges one-size-fits-all biomarker approaches and paves the way for more personalised, precision-based strategies in chronic pain diagnosis and management.
Authors
- Antonio R. Artalejo (ORCID: https://orcid.org/0000-0001-9720-9190)
- Vicente Mustieles (ORCID: https://orcid.org/0000-0002-2010-5438)
- Luis Miguel García‐Segura (ORCID: https://orcid.org/0000-0002-2450-2916)
- Mercedes Sotos‐Prieto (ORCID: https://orcid.org/0000-0001-9127-2586)
- Rosario Ortolá (ORCID: https://orcid.org/0000-0001-6952-9533)
- Esther García‐Esquinas (ORCID: https://orcid.org/0000-0002-8688-5174)
- Anna C. Koni
- Fernando Rodríguez-Artalejo
- S. Cabello‐Plan
Institutions
- Madrid Institute for Advanced Studies (ES)
- Universidad Complutense de Madrid (ES)
- Harvard University (US)
- Stockholm University (SE)
- Universidad de Granada (ES)
- Universidad Nacional de Educación a Distancia (ES)
- Instituto Cajal (ES)
- Instituto de Salud Carlos III (ES)
- Karolinska Institutet (SE)
- Instituto de Investigación Biosanitaria de Granada (ES)
- IMDEA Food (ES)
- Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES)
- Universidad Autónoma de Madrid (ES)
Publication Details
- Journal
- European Journal of Pain
- Published
- 2025-04-13
- DOI
- https://doi.org/10.1002/ejp.70014
- Citations
- 7
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 6.36
Funders
- Instituto de Salud Carlos III
- European Regional Development Fund
- European Social Fund