Identification and Validation of Circadian Rhythm‐Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning
Six genes (CCND1, FOXO1, FRMD8, NTRK2, PRRT1 and TFPI) linked to circadian rhythms associated with IVDD progression, together with immunity. The identification of these DEGs may provide new insights for the diagnosis and treatment of IVDD.
Authors
- Yongbo Zhang (ORCID: https://orcid.org/0009-0008-3239-8013)
- Sheng Yang (ORCID: https://orcid.org/0000-0003-3657-8771)
- Liuyang Chen
- Rui Dai (ORCID: https://orcid.org/0009-0008-2257-5039)
- Liang Zhang
- Hua Sun
Institutions
- Dalian Medical University (CN)
- Northern Jiangsu People's Hospital (CN)
- Yangzhou University (CN)
Publication Details
- Journal
- JOR Spine
- Published
- 2025-04-13
- DOI
- https://doi.org/10.1002/jsp2.70066
- Citations
- 2
- Primary Topic
- Healthcare and Venom Research
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Dalian Medical University