Necrostatin‐1 attenuates oral squamous cell carcinoma by modulating tumour immune response in mice
In summary, blocking the necroptosis pathway alters the tumour microenvironment (TME) and inhibits the progression of OSCC. Targeting necroptosis could be an effective therapy for treating OSCC in a clinical setup.
Authors
- Piyush Khandelia (ORCID: https://orcid.org/0000-0003-0641-0257)
- L. Saravanan
- Vikram Gota (ORCID: https://orcid.org/0000-0001-6348-6667)
- Ashutosh Mahale (ORCID: https://orcid.org/0000-0002-9238-8262)
- Onkar P. Kulkarni (ORCID: https://orcid.org/0000-0002-8877-0573)
Institutions
- Tata Memorial Hospital (IN)
- Advanced Centre for Treatment, Research and Education in Cancer (IN)
- Birla Institute of Technology and Science, Pilani (IN)
Publication Details
- Journal
- Fundamental and Clinical Pharmacology
- Published
- 2025-04-13
- DOI
- https://doi.org/10.1111/fcp.70008
- Citations
- 3
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- Indian Council of Medical Research
- Science and Engineering Research Board