Dietary vitamin intake and its association with hypertension (HPT) among Malaysian adults
This study aims to investigate the association between dietary vitamin (A, B<sub>6</sub>, B<sub>9</sub>, B<sub>12</sub>, C, E, and K) intake and hypertension (HPT) among Malaysian adult population. This is a cross-sectional analysis of baseline data from a population-based cohort of 10,031 participants from the Malaysia arm of the Prospective Urban and Rural Epidemiology (PURE) study. Participants were classified as having HPT if they reported a diagnosis of high blood pressure (systolic blood pressure (SBP)/diastolic blood pressure (DBP) > 140/90). Participants' usual dietary intake was assessed using a validated food frequency questionnaire. Vitamin (A, B<sub>6</sub>, B<sub>9</sub>, B<sub>12</sub>, C, E, and K) intake was calculated using nutrient databases. The Mann-Whitney U test was used to assess differences in vitamin intake between the HPT groups. This study found that the prevalence of HPT among 10,031 respondents was 43.5%. The overall dietary intake of vitamins A and C was adequate, but the intake of vitamins B<sub>6</sub>, B<sub>9</sub>, B<sub>12</sub>, E, and K was inadequate compared to Malaysia's Recommended Nutrient Intakes (RNI). The intake of vitamins A, B<sub>6</sub>, B<sub>9</sub>, B<sub>12</sub>, E, and K was significantly lower among patients with HPT compared to those without HPT (p-value < 0.001). This study found that the Malaysian adult population is not receiving sufficient intake of vitamins B<sub>6</sub>, B<sub>9</sub>, B<sub>12</sub>, E, and K from their diet. Improving vitamin intake can be achieved through nutrition education, a diet that includes a variety of healthy foods, and food fortification and supplementation.
Authors
- Nurul Hafiza Ab Razak (ORCID: https://orcid.org/0000-0003-1446-8889)
- Khairul Hazdi Yusof (ORCID: https://orcid.org/0000-0002-7205-8258)
- Azmi Mohd Tamil (ORCID: https://orcid.org/0000-0002-1657-3351)
- Boon‐Peng Hoh (ORCID: https://orcid.org/0000-0001-9249-4965)
- Mohd Hasni Jaáfar (ORCID: https://orcid.org/0000-0003-0007-6008)
- Najihah Zainol Abidin (ORCID: https://orcid.org/0000-0003-2742-8747)
- Rosnah Ismail (ORCID: https://orcid.org/0000-0002-8178-3822)
- Zaleha Md Isa (ORCID: https://orcid.org/0000-0003-4850-901X)
- Nafiza Mat Nasir (ORCID: https://orcid.org/0000-0002-8022-5757)
- Noor Hassim Ismail (ORCID: https://orcid.org/0000-0003-1547-7904)
Institutions
- Management and Science University (MY)
- University Kebangsaan Malaysia Medical Centre (MY)
- University of Malaya (MY)
- Hospital Sungai Buloh (MY)
- National University of Malaysia (MY)
Publication Details
- Journal
- Scientific Reports
- Published
- 2025-04-13
- DOI
- https://doi.org/10.1038/s41598-025-89749-9
- Citations
- 1
- Primary Topic
- Nutritional Studies and Diet
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- AstraZeneca
- GlaxoSmithKline
- Sanofi
- Heart and Stroke Foundation of Canada
- Ontario Ministry of Health and Long-Term Care
- Ministério da Ciência, Tecnologia e Inovação
- Servier
- Canadian Institutes of Health Research