Cost-utility analysis of olaparib assisted targeted therapy for BRCA mutation HER2-negative early breast cancer in China and in the United States

When evaluated in the context of healthcare economics in both China and the United States, the implementation of an Olaparib-based treatment strategy for early-stage HER2-negative breast cancer with BRCA mutations does not present a cost-effective solution in either nation.

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Publication Details

Journal
Cost Effectiveness and Resource Allocation
Published
2025-04-13
DOI
https://doi.org/10.1186/s12962-025-00617-9
Citations
3
Primary Topic
PARP inhibition in cancer therapy
Type
article
Field-Weighted Citation Impact
3.14

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article

Cost-utility analysis of olaparib assisted targeted therapy for BRCA mutation HER2-negative early breast cancer in China and in the United States

Jiaqin Cai, Jie Zhuang, Hong Sun, Chenxia Xu et al.
3 citations
Cost Effectiveness and Resource Allocation
PARP inhibition in cancer therapy
3.14
article

Cost-utility analysis of olaparib assisted targeted therapy for BRCA mutation HER2-negative early breast cancer in China and in the United States

Jiaqin Cai, Jie Zhuang, Hong Sun, Chenxia Xu, Jeannie Shen, Xiaoxia Wei
article en
3 citations

Abstract

When evaluated in the context of healthcare economics in both China and the United States, the implementation of an Olaparib-based treatment strategy for early-stage HER2-negative breast cancer with BRCA mutations does not present a cost-effective solution in either nation.

Cost Effectiveness and Resource AllocationVol. 23(1)
Fujian Medical University (CN), Fujian Provincial Hospital (CN), Union Hospital (CN)
Fujian Provincial Health Technology Project
Good health and well-being
Openalex Percentile: Top 8%
PARP inhibition in cancer therapy
3.14
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