Optimizing Photothermal Performance of Gold Nanorod Conjugates Through Near Infrared Dye Molecule for Photothermal Applications

This study explores a novel approach to amplify the photothermal efficiency of gold nanorod conjugates (GNRC) for photothermal applications. By combining the joule heat of gold nanorods (GNRs) with the non-radiative coupling of excited dye molecules, we have achieved a 1.9-fold increase in photothermal efficiency compared to bare GNRs. This synergistic effect enables us to reach target temperatures with reduced nanoparticle (NP) concentration or lower-powered near-infrared (NIR) light sources. The study introduces the concept of non-radiative decay engineering, demonstrating its potential to revolutionize photothermal treatments. Our work opens doors for tailored, more efficient photothermal therapies and encourages further exploration of this intriguing field.