NEUTROPHIL LYMPHOCYTE RATIO AND PLATELETS LYMPHOCYTES RATIO WITH GLYCEMIC CONTROL IN PATIENTS WITH DIABETES MELLITUS

Background:Diabetes mellitus (DM) is a long-term health problem, which causes swelling of atissue. The Neutrophil-to-Lymphocyte Ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) are promising biomarkers of the blood sugar level in the type 2 diabetes mellitus (T2DM) Patients. The purpose of the study was to evaluate the relationship between NLR, PLR, and glycemic control in T2DM patients. Material and Methods: The inclusion of 102 T2DM patients who had HbA1c levels <7% and >7% was based on a cross-sectional study carried out at Allama Iqbal Medical College/Jinnah Hospital Lahore from May to December 2024. Thereafter, the NLR and PLR were calculated through the blood counts. The most important results were the change in the blood sugar levels and HbA1c.Results: Type 2 diabetes mellitus (HbA1c>7%) was noted in 63% of the patients, and it was correlated with decrease in NLR and PLR (p<0.001. NLR showed a positive correlation with HbA1c (r=0.45) and PLR a figure of 0.48. Conclusion: A higher number of NLR and PLR in the body could lead to the development of poor glycemic regulation in T2DM patients, identifying them as valuable diagnostic tools for disease management and their benefits.