SOD1-ALS mimicking an inflammatory neuropathy: a case report
We present the case of a 36-year-old patient with a rapidly progressing SOD1-ALS, who was initially diagnosed as inflammatory acute motor axonal neuropathy due to contrast-enhancement of the lumbar spinal cord and a pure secondary motor neuron phenotype. Since the initiation of tofersen, disease progression and neurofilament levels impressively declined.
Authors
- René Günther (ORCID: https://orcid.org/0000-0003-0329-5644)
- Hanna Sophie Lapp (ORCID: https://orcid.org/0000-0001-6733-7861)
Institutions
- German Center for Neurodegenerative Diseases (DE)
- Technische Universität Dresden (DE)
Publication Details
- Journal
- Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Published
- 2025-04-12
- DOI
- https://doi.org/10.1080/21678421.2025.2488296
- Citations
- 2
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 2.78