Early Intervention with Mepolizumab, Corticosteroids, and Intravenous Immunoglobulin for Dupilumab-Triggered Eosinophilic Granulomatosis with Polyangiitis: A Case Report
This case emphasizes the importance of monitoring preexisting MPO-ANCA and blood eosinophils before and during dupilumab therapy. Early intervention with mepolizumab combined with conventional therapy is considered an optimal treatment strategy for dupilumab-triggered EGPA.
Authors
- Kazuo Kasahara (ORCID: https://orcid.org/0000-0001-5551-1543)
- Koichiro Kamio (ORCID: https://orcid.org/0000-0002-6870-9548)
- Yosuke Tanaka (ORCID: https://orcid.org/0000-0003-4965-7030)
- Shota Kaburaki (ORCID: https://orcid.org/0000-0002-1194-087X)
- Masahiro Seike (ORCID: https://orcid.org/0000-0002-1572-5472)
- Toru Tanaka (ORCID: https://orcid.org/0000-0002-1054-9211)
Institutions
- Nippon Medical School (JP)
Publication Details
- Journal
- Journal of Asthma and Allergy
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/jaa.s513640
- Citations
- 1
- Primary Topic
- Eosinophilic Disorders and Syndromes
- Type
- article
- Field-Weighted Citation Impact
- 1.67